Analysis of the effect of sampling swabs in the detection of cervical cancer
Date: 2021-12-14
At present, the cervical swabs used on the market mainly include inverted V-shaped cervical swabs, nylon fiber cell brushes, and flocked nylon sampling swabs. The former function is between the scraper and the cervical swab, and the exfoliated cells are collected by using the serrated structure of the front section. Nylon fiber cell brushes have flexible fibers perpendicular to the handle for easy access to the neck canal. The flocked nylon swab is a sampling swab made by spraying flocked flock on the ABS rod, which can extract the sample and adsorb it close to the surface of the sampling head, and can be released completely and quickly. Features such as small damage.
Regardless of which HPV test is used, exfoliated cells from the cervical epithelium are required as the test sample. The earliest clinical use of cotton swabs as a sampler for cervical epithelial exfoliation cells, but due to the small friction of cotton, the amount of cells collected is insufficient, and the water absorption of cotton often leads to dehydration and degeneration of cells, which affects the observation of cells. In addition, cotton often absorbs more mucus, which leads to accumulation of cells during smearing, which makes sample preparation and sample preservation more difficult. Although the shovel-shaped scraper avoids the protection shortcomings of cotton swabs, the amount of cells collected is still low, resulting in high false-negative results and a high missed diagnosis rate. In recent years, experts have strongly recommended the use of cervical swabs as a sampler for cervical exfoliated cells to collect exfoliated cells from the cervical squamocolumnar junction.
Some studies have found that HPV testing can lead to emotional reactions such as fear and anxiety in women, and the reasons are related to the sampling site and testing method. Different genital tract sites have differences in viral load and low-risk HPV infection rates. Different HPV detection methods have different sensitivity and specificity. During HPV testing, sampling tools with high collection efficiency, safety, stability, and simple operation should be selected as far as possible, and a sufficient amount of samples should be collected from the cervix as much as possible. HPV detection accuracy.
Regardless of which HPV test is used, exfoliated cells from the cervical epithelium are required as the test sample. The earliest clinical use of cotton swabs as a sampler for cervical epithelial exfoliation cells, but due to the small friction of cotton, the amount of cells collected is insufficient, and the water absorption of cotton often leads to dehydration and degeneration of cells, which affects the observation of cells. In addition, cotton often absorbs more mucus, which leads to accumulation of cells during smearing, which makes sample preparation and sample preservation more difficult. Although the shovel-shaped scraper avoids the protection shortcomings of cotton swabs, the amount of cells collected is still low, resulting in high false-negative results and a high missed diagnosis rate. In recent years, experts have strongly recommended the use of cervical swabs as a sampler for cervical exfoliated cells to collect exfoliated cells from the cervical squamocolumnar junction.
Some studies have found that HPV testing can lead to emotional reactions such as fear and anxiety in women, and the reasons are related to the sampling site and testing method. Different genital tract sites have differences in viral load and low-risk HPV infection rates. Different HPV detection methods have different sensitivity and specificity. During HPV testing, sampling tools with high collection efficiency, safety, stability, and simple operation should be selected as far as possible, and a sufficient amount of samples should be collected from the cervix as much as possible. HPV detection accuracy.
