What are the prohibited materials for throat swabs?
Date: 2021-12-14
What materials are banned for throat swabs? We know that the throat swab is in direct contact with the sampling site, and the material of the sampling head is closely related to the subsequent detection.
The sampling swab head should be made of PE synthetic fiber or man-made fiber. Calcium alginate sponge or wooden stick swabs (including bamboo sticks) cannot be used, and cotton products cannot be used for the swab head, because the fibers of cotton are not suitable for protein The adsorption is strong, and it is not easy to be eluted into the subsequent preservation solution; and the broken wooden sticks or bamboo sticks containing calcium alginate and wooden components will also adsorb proteins after being soaked in the preservation solution, and may even affect the subsequent PCR reaction. have inhibitory effect.
It is recommended to use synthetic fibers such as PE fiber, polyester fiber, and polypropylene fiber for the material of the swab head. Nasopharyngeal swab manufacturers do not recommend using natural fibers such as cotton, nor do they recommend nylon fibers, because nylon fibers (similar to toothbrush heads) have poor water absorption, which will lead to insufficient sampling and affect the initial detection rate.
Calcium alginate additives cannot be added to the material for making the swab handle; wooden sticks or bamboo sticks are not recommended. In short, the sampling swab should ensure the sampling amount and release amount, and the selected material must not contain substances that affect the subsequent detection.
The sampling swab head should be made of PE synthetic fiber or man-made fiber. Calcium alginate sponge or wooden stick swabs (including bamboo sticks) cannot be used, and cotton products cannot be used for the swab head, because the fibers of cotton are not suitable for protein The adsorption is strong, and it is not easy to be eluted into the subsequent preservation solution; and the broken wooden sticks or bamboo sticks containing calcium alginate and wooden components will also adsorb proteins after being soaked in the preservation solution, and may even affect the subsequent PCR reaction. have inhibitory effect.
It is recommended to use synthetic fibers such as PE fiber, polyester fiber, and polypropylene fiber for the material of the swab head. Nasopharyngeal swab manufacturers do not recommend using natural fibers such as cotton, nor do they recommend nylon fibers, because nylon fibers (similar to toothbrush heads) have poor water absorption, which will lead to insufficient sampling and affect the initial detection rate.
Calcium alginate additives cannot be added to the material for making the swab handle; wooden sticks or bamboo sticks are not recommended. In short, the sampling swab should ensure the sampling amount and release amount, and the selected material must not contain substances that affect the subsequent detection.
